abstract：:To examine longitudinally the effect of diabetes on bone structure and metabolism, we measured bone mineral density (BMD) and turnover markers in 26 type 1 (mean age 49 years) and 27 type 2 (mean age 65 years) diabetic patients without known osteoporosis from a community-based sample at baseline and 5 years later. In ...

journal_title：Acta diabetologica

authors： Hamilton EJ,Rakic V,Davis WA,Paul Chubb SA,Kamber N,Prince RL,Davis TM

更新日期：2012-04-01 00:00:00

abstract：:In late twentieth century, Ruderman and Reaven showed that insulin resistance might be fundamental to metabolic syndrome (MetS) which means a constellation of obesity-related metabolic derangements predisposing to type 2 diabetes and cardiovascular disease. In 2001, user-friendly National Cholesterol Education Program...

journal_title：Acta diabetologica

authors： Oda E

更新日期：2012-04-01 00:00:00

abstract：:We hypothesize that type 2 diabetic patients with different phenotypes may show different response to incretin-based therapies. Therefore, we tested whether the presence of metabolic syndrome (MS) influences glycemic response to these drugs. We prospectively followed 211 patients, treated with the GLP-1 analog exenati...

journal_title：Acta diabetologica

authors： Fadini GP,de Kreutzenberg SV,Gjini R,Avogaro A

更新日期：2011-09-01 00:00:00

abstract：:The objective of this study is to explore the mechanism of oxidative stress induced by intermittent high glucose in porcine iliac endothelial cells (PIECs). The PIECs were exposed to intermittent or constant high glucose for 3 or 6 days, and the mean fluorescent intensity (MFI) was measured via intracellular reactive ...

journal_title：Acta diabetologica

authors： Ge QM,Dong Y,Zhang HM,Su Q

更新日期：2010-12-01 00:00:00

abstract：:We analysed the risk factors associated with diabetic complications in the cohort of patients assisted by a type 2 diabetes mellitus (T2DM) shared-care program. We analysed registry data from 16,136 T2DM patients. Of them, 4,781 had microangiopathy, 3,469 CV events. They were 70.5 ± 17.1 years old, 50% were male, dise...

journal_title：Acta diabetologica

authors： Ciardullo AV,Daghio MM,Bevini M,Feltri G,Novi D,Fattori G,Borsari S,Donato CD

更新日期：2010-12-01 00:00:00

abstract：:The aim of this article is to investigate the relation of the anti-inflammatory effect of pioglitazone with cardiac autonomic function and metabolic control in diabetic patients. In this prospective open label trial, 36 type 2 diabetic patients (age 60 ± 10, 20 M) without overt cardiovascular disease were randomized t...

journal_title：Acta diabetologica

authors： Nerla R,Pitocco D,Zaccardi F,Scalone G,Coviello I,Mollo R,Ghirlanda G,Lanza GA,Crea F

更新日期：2010-12-01 00:00:00

abstract：:Studies suggest that diabetes may specifically elevate the risk of sudden cardiac death in excess of other heart disease outcomes. In this study, we examined the association of type 2 diabetes with the incidence of sudden cardiac death when compared to the incidence of non-sudden cardiac death and non-fatal myocardial...

journal_title：Acta diabetologica

authors： Kucharska-Newton AM,Couper DJ,Pankow JS,Prineas RJ,Rea TD,Sotoodehnia N,Chakravarti A,Folsom AR,Siscovick DS,Rosamond WD

更新日期：2010-12-01 00:00:00

abstract：:Hyperglycaemia caused by stress and inflammation is common during critical illness. We hypothesised that a latent glucose metabolism disturbance contributes to development of hyperglycaemia and that those patients have increased risk for diabetes. We included patients with sepsis, acute coronary syndrome and acute hea...

journal_title：Acta diabetologica

authors： Gornik I,Vujaklija A,Lukić E,Madžarac G,Gašparović V

更新日期：2010-12-01 00:00:00

abstract：:The objective of this study was to describe spatial and space-time patterns of type 1 diabetes in children less than 15 years old, diagnosed between 2000 and 2005 with residence in the Metropolitan Region of Chile. Knox and Mantel tests were used to detect space-time interaction between cases. An ecological Bayesian m...

journal_title：Acta diabetologica

authors： Torres-Avilés F,Carrasco E,Icaza G,Pérez-Bravo F

更新日期：2010-09-01 00:00:00

abstract：:Cyclosporin and methotrexate administration induces remission of type 1 diabetes mellitus. Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). Its usefulness was limited by its toxicity. Since methotrexate (mtx) and cyclo synergistically inhibit ...

journal_title：Acta diabetologica

authors： Sobel DO,Henzke A,Abbassi V

更新日期：2010-09-01 00:00:00

abstract：:The aim of the study was to report the prevalence of obesity indices in individuals with diabetes and find out their association with diabetic retinopathy in the urban Indian population. Subjects (n = 1,414) were recruited from Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular Genetics Study (SN-DREAM...

journal_title：Acta diabetologica

authors： Raman R,Rani PK,Gnanamoorthy P,Sudhir RR,Kumaramanikavel G,Sharma T

更新日期：2010-09-01 00:00:00

abstract：:Administration of exogenous insulin for the treatment of diabetes is often accompanied by the development of insulin antibodies (IA). These antibodies may affect the patient's requirement for insulin by acting as an insulin binding reservoir. The improvement of insulin purification in the 1970s and the development of ...

journal_title：Acta diabetologica

authors： Oak S,Phan TH,Gilliam LK,Hirsch IB,Hampe CS

更新日期：2010-06-01 00:00:00

abstract：:A cross-sectional descriptive study was done on patients recently entered into the National Diabetes Registry in Eritrea where the prevalence was estimated to be 2.2% based on patient information in 2004. Of the 627 patients with diabetes, two thirds were type 2. Although type 1 had poorer control (42.9%) than type 2 ...

journal_title：Acta diabetologica

authors： Seyum B,Mebrahtu G,Usman A,Mufunda J,Tewolde B,Haile S,Kosia A,Negassi E

更新日期：2010-03-01 00:00:00

abstract：:The purpose of this study was to compare bioelectrical impedance analysis (BIA) to hydrostatic weighing (HW) in male weight lifters and body builders. Twenty-two male body builders and weight lifters, 23 +/- 3 years of age (mean +/- SD), were studied to determine the efficacy of BIA to HW in this population. Subjects ...

journal_title：Acta diabetologica

authors： Volpe SL,Melanson EL,Kline G

更新日期：2010-03-01 00:00:00

abstract：:This study was aimed at the assessment of incidence of malignancies in type 2 diabetic patients treated with different sulphonylureas. A matched case-control study was performed. Cases were 195 diabetic patients aged 69.0 +/- 9.2 years who had an incident malignancy. Controls were 195 diabetic patients, unaffected by ...

journal_title：Acta diabetologica

authors： Monami M,Lamanna C,Balzi D,Marchionni N,Mannucci E

更新日期：2009-12-01 00:00:00

abstract：:Diabetic neuropathy is a significant complication of chronic diabetes. We wished to discover whether we were successfully identifying patients who had developed neuropathic problems. Specifically, Diabetologists are traditionally poor at asking about erectile dysfunction (ED) and patients themselves are not always for...

journal_title：Acta diabetologica

authors： Grant PS,Lipscomb D

更新日期：2009-12-01 00:00:00

abstract：:The purpose of this study is to identify the recent characteristics and the developments of therapeutic education in diabetes through an analysis of the international articles published from 2004 to 2007. Studies were selected from several databases: Medline, Embase, Eric, Cochrane central database, using the followin...

journal_title：Acta diabetologica

authors： Albano MG,Crozet C,d'Ivernois JF

更新日期：2008-12-01 00:00:00

abstract：:To evaluate ex vivo/in vitro the binding and dissociation characteristics and the level of crossreactivity of insulin antibodies and insulin autoantibodies directed to three different insulin molecules (human, bovine and porcine insulin). In this study sera from 17 diabetic patients were included, who were exclusively...

journal_title：Acta diabetologica

authors： Jaeger C,Winter S,Eckhard M,Hardt P,Brendel MD,Bretzel RG

更新日期：2008-09-01 00:00:00

abstract：:Sourdough bread has been reported to improve glucose metabolism in healthy subjects. In this study postprandial glycaemic and insulinaemic responses were evaluated in subjects with impaired glucose tolerance (IGT) who had a meal containing sourdough bread leavened with lactobacilli, in comparison to a reference meal c...

journal_title：Acta diabetologica

authors： Maioli M,Pes GM,Sanna M,Cherchi S,Dettori M,Manca E,Farris GA

更新日期：2008-06-01 00:00:00

abstract：:To determine the impact of glargine insulin therapy with different nutritional models on key parameters of diabetes including quality of life, behavior in children and adolescents with type 1 diabetes. Age, duration of diabetes, HbA1c, anthropometric data and episodes of severe hypoglycemia were taken from patients' c...

journal_title：Acta diabetologica

authors： Goksen D,Darcan S,Buyukinan M,Köse T,Erermis S,Coker M

更新日期：2008-03-01 00:00:00

abstract：:The aim of this study was to evaluate the prevalence of thyroid autoantibodies and clinical significance of thyroid autoimmunity in children with the diagnosis of diabetes mellitus type 1. The study group comprised 222 children all with newly diagnosed diabetes mellitus type 1 (122 boys) with a mean age 9.92 +/- 4.5 y...

journal_title：Acta diabetologica

authors： Machnica L,Osior A,Jarosz-Chobot P,Deja G,Polanska J,Otto-Buczkowska E

更新日期：2008-03-01 00:00:00

abstract：:Serum gamma-glutamyl transferase (gamma-GT), a marker of oxidative stress, predicts morbidity and mortality from cardiovascular disease. Plasma total homocysteine (tHcy), a pro-oxidant and also an independent risk factor for cardiovascular disease, correlates with gamma-GT among some populations. It is not known wheth...

journal_title：Acta diabetologica

authors： Sakuta H,Suzuki T,Ito T

更新日期：2007-12-01 00:00:00

abstract：:The objective is to assess the effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar rats, 8-week-old, were categorized into four groups, which were the control (n = 9), diabetes (n = 9), infliximab-treated diabetes (n = 10), and FR167653-treated diabetes (n = 9) groups...

journal_title：Acta diabetologica

authors： Moriwaki Y,Inokuchi T,Yamamoto A,Ka T,Tsutsumi Z,Takahashi S,Yamamoto T

更新日期：2007-12-01 00:00:00

abstract：:The aim of this study was to compare the efficacy of treatment with insulin alone, insulin plus acarbose, insulin plus metformin, or insulin plus rosiglitazone in type 2 diabetic subjects who were previously on insulin monotherapy, and to evaluate the effects of these treatments on cardiovascular risk factors includin...

journal_title：Acta diabetologica

authors： Yilmaz H,Gursoy A,Sahin M,Guvener Demirag N

更新日期：2007-12-01 00:00:00

abstract：:We investigated the effect of sub-chronic soybean oil (SO) treatment on the insulin secretion and fatty acid composition of islets of Langerhans obtained from Goto-Kakizaki (GK), a model of type 2 diabetes, and normal Wistar rats. We observed that soybean-treated Wistar rats present insulin resistance and defective is...

journal_title：Acta diabetologica

authors： Nunes E,Peixoto F,Louro T,Sena CM,Santos MS,Matafome P,Moreira PI,Seiça R

更新日期：2007-09-01 00:00:00

abstract：:The aim of this study was to investigate the influence of homocysteine (hcy) levels on endothelial function by the method of brachial artery ultrasonography and their relation with microvascular complications in type 2 diabetes mellitus (T2DM) patients without macrovascular disease. Fifty-nine T2DM patients with a mea...

journal_title：Acta diabetologica

authors： Karabag T,Kaya A,Temizhan A,Koç F,Yavuz S,Cam S

更新日期：2007-06-01 00:00:00

abstract：:The objective of the study was to evaluate the association between infectious diseases and other events pertaining to childhood medical history and type 1 diabetes. A case-control study was carried out, taking as cases 159 type 1 diabetic patients (0-29 years) recorded from 1988 to 2000 within the population registry ...

journal_title：Acta diabetologica

authors： Tenconi MT,Devoti G,Comelli M,Pinon M,Capocchiano A,Calcaterra V,Pretti G,Pavia T1DM Registry Group.

更新日期：2007-03-01 00:00:00

abstract：:Insulin resistance is a major factor in the pathogenesis of type 2 diabetes mellitus (T2DM) and is related to the fatty acid profile of the plasma membranes. The purpose of the present study was to investigate fatty acid composition and cholesterol content of cell membranes in patients with type 2 diabetes and, thus, ...

journal_title：Acta diabetologica

authors： Bakan E,Yildirim A,Kurtul N,Polat MF,Dursun H,Cayir K

更新日期：2006-12-01 00:00:00

abstract：:The objective of the study was to determine the prevalence of known diabetes among elderly subjects receiving nursing care in a north Norwegian population, to screen for new cases using HbA1c measurement and to evaluate the quality of care for those with diabetes. Men and women, with and without known diabetes, above ...

journal_title：Acta diabetologica

authors： Jorde R,Hagen T

更新日期：2006-08-01 00:00:00

abstract：:The aim of this study was to analyse the effect of the new oral antidiabetic drug repaglinide on antioxidant factors and lipid peroxidation in tissues of alloxan-induced diabetic rabbits after 4 and 8 weeks treatment. The activity of superoxide dismutase (diabetic vs. control values, mean+/-S.E.M., p<0.05) in diabetic...

journal_title：Acta diabetologica

authors： Gumieniczek A

更新日期：2005-06-01 00:00:00

abstract：:Cardiovascular risk is determined by multiple risk factors, all of which greatly increase the chance of morbidity and mortality. So-called "normal" levels of these factors are not biologically normal, so current strategy is based on estimations of a person's global cardiovascular risk, and then using appropriate combi...

journal_title：Acta diabetologica

authors： Sleight P

更新日期：2005-04-01 00:00:00

abstract：:Comparing macrophage-derived cytokine and nitric oxide (NO) profiles in type I and type II diabetes mellitus (DM); and determining whether thymoquinone (TQ) has any modulatory effect were the main objectives of the present study. Peritoneal macrophages have been collected from Otsuka Long-Evans Tokushima Fatty (OLETF)...

journal_title：Acta diabetologica

authors： El-Mahmoudy A,Shimizu Y,Shiina T,Matsuyama H,Nikami H,Takewaki T

更新日期：2005-03-01 00:00:00

abstract：:Overload of reactive oxygen species during diabetes is known to impair cellular homeostasis and to promote deterioration of membrane function in the organism. The aim of the present study was to examine the effect of dietary supplementation with the pyridoindole atioxidant stobadine on functional properties of the ren...

journal_title：Acta diabetologica

authors： Vrbjar N,Strelková S,Stefek M,Kyselová Z,Gajdosíková A

更新日期：2004-12-01 00:00:00

abstract：:Diabetes mellitus, the most common serious metabolic disorder, is characterized by functional and structural changes in the peripheral and central nervous systems. Glial cells provide structural and metabolic support for retinal neurons. During diabetes, one of the early pathogenic events is retinal glial reactivity. ...

journal_title：Acta diabetologica

authors： Baydas G,Tuzcu M,Yasar A,Baydas B

更新日期：2004-09-01 00:00:00

abstract：:Anorectic patients who achieve complete recovery from the eating disorder can obtain a favorable psychosocial outcome but the long-term nutritional outcome is ill-defined. We investigated the time course of total and distrectual body composition during and after refeeding in 32 female patients with anorexia nervosa. P...

journal_title：Acta diabetologica

authors： Bertoli S,Corradi E,Vangeli V,Tarlarini P,Salvatori GC,Gentile MG,Testolin G,Battezzati A

更新日期：2004-03-01 00:00:00

abstract：:Cardiovascular diseases represent, today, the principal cause of mortality in the general population, especially in subjects with type 2 diabetes mellitus. In these patients the risk of death from cardiovascular diseases is equal to that of non-diabetic subjects with a previous episode of myocardial infarction. Many f...

journal_title：Acta diabetologica

authors： Palumbo F,Bianchi C,Miccoli R,Del Prato S

更新日期：2003-12-01 00:00:00

abstract：:Although the effects of sex, ageing, height, race, and current and past health on pulmonary function tests have been described, only non-significant associations have been observed between body weight and lung function among healthy persons after having accounted for the effects of age and height. However, few studies...

journal_title：Acta diabetologica

authors： Maiolo C,Mohamed EI,Carbonelli MG

更新日期：2003-10-01 00:00:00

abstract：:The recent efforts in the study of fetal compartments could help us to a better recognition of the proper fetal growth and well being. Fat content correlates directly with energy stores. Fat mass and lean body mass is often used in the nutritional assessment of the individual. Moreover chromosomal abnormalities may be...

journal_title：Acta diabetologica

authors： Valensise H,Larciprete G,Arduini D,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：:The objective of this study was to verify the impact of various sports on body cell mass (BCM). Ninety-eight male subjects, 17-33 years of age, participated in the study. The sample included athletes from three professional Italian football (soccer) teams, representing three different divisions (A, n=16; B, n=14; and ...

journal_title：Acta diabetologica

authors： Andreoli A,Melchiorri G,Brozzi M,Di Marco A,Volpe SL,Garofano P,Di Daniele N,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：:The assessment of body composition and energy requirements is important for the nutrition of healthy and pathological states such as gastrointestinal disorders, which are known to be associated with abnormalities in body composition among persons with malnutrition and malabsorption. Careful monitoring of body composit...

journal_title：Acta diabetologica

authors： De Lorenzo A,Maiolo C,Mohamed EI,Casini A

更新日期：2003-10-01 00:00:00